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Preparing for treatment

Actor portrayal.

Make a few changes to your daily routine to get the most out of treatment

While you should expect to have some side effects during treatment, there are a few important steps that you can add into your daily routine to lower your risk.

These steps have been proven to make a positive difference for people taking  RYBREVANT FASPRO™ or RYBREVANT® .

At-Home Care Video

Watch this video to learn about some ways to take care of yourself while on treatment by adding a few steps to your daily routine.

Treatment Experience Tips Flashcard

Daily tips and reminders to help you reduce your risk of side effects.

Learn Tips From a RYBREVANT® Patient

Learn from Lexi, a mother of three, as she talks about how she manages her side effects on RYBREVANT®.

Choose the tab for your treatment below to see how you can prepare for treatment.

RYBREVANT FASPRO™ injections + LAZCLUZE®
RYBREVANT® infusions + LAZCLUZE®
Before treatment

Tips to help you prepare for your RYBREVANT FASPRO™ injection appointments

Drink plenty of water the day before, and have a good breakfast on injection day.
Wear loose clothes for comfort and so your care team can easily reach your abdomen or stomach.
Pay close attention to how you feel during an injection, and make sure to tell your care team if you experience any discomfort. They know how to help.
Your care team will give you allergy medicine, a fever reducer, and a steroid to help reduce the risks of serious side effects from the injection.
Consider setting up transportation to and from your appointment. You will receive medicine before your injection that may make you drowsy. If you need help setting up a ride, reach out to your family and friends.

If you have any other questions about your injections, ask your care team.

At-home care

Daily, at-home steps to manage your treatment experience

These steps may lower the chances of skin-related side effects, such as rash or infected skin around the nail or other side effects. Talk to your doctor about what steps are right for you.

medication red icon

Additional medicines

  • Oral antibiotics (for the first 3 months of treatment) followed by an antibiotic lotion for your scalp (for the next 9 months) may be prescribed to reduce risk of skin-related side effects
  • Medicine to lower your risk of blood clots will be prescribed for the first 4 months of treatment

Make sure to tell your doctor about any other medicines you are taking. Consider using a pill box to help you organize your medicines.

Mild, ceramide-based moisturizer (such as La Roche-Posay Lipikar or CeraVe†‡)

Use on your face and body (except scalp) at least once a day.

Limit direct exposure to sunlight

Wear protective clothing and broad-spectrum sunscreen with SPF ≥30.

finger red icon

Antiseptic cleanser (such as chlorhexidine 4%)

Use to wash your hands and feet once a day.

†Talk to your doctor about what is right for you.

‡All trademarks are property of their respective owners.

Other tips to help throughout treatment

  • Consider bathing/
    showering with warm or cool water (not hot water)
  • Use mild soaps and shampoos for sensitive
    skin
  • Use laundry detergents made for sensitive skin and without perfumes
  • Wear soft, loose-fitting clothing
  • Wear gloves during activities that could cause nail infection (for example, cleaning)
  • Eat a balanced diet
  • Talk to your doctor about activities that feel right for you
  • Seek out support from your family, friends, care team, and/or support groups

Talk to your care team to understand if these tips are right for you.

During treatment

Your care team can help manage or reduce the risk of RYBREVANT FASPRO™ side effects

It's important to tell your care team about side effects right away if you:

  • First experience symptoms of side effects
  • Feel that the side effects are affecting daily activities
  • Have been treating side effects according to your doctor's instructions but they do not improve

Pausing, decreasing the dose, or stopping treatment may be needed in some cases to help manage side effects.

medication red icon

Tell your doctor if you are pregnant or plan to become pregnant. RYBREVANT FASPRO™ injections and LAZCLUZE® can harm your unborn baby.

Before each infusion

Tips to help you prepare for your RYBREVANT® infusion appointments

Drink plenty of water the day before, and have a good breakfast on infusion day.
Bring a pillow and blanket for extra comfort.
Infusions can last several hours, so make sure you’ve set aside enough time for your appointment. Ask your care team about how long your infusion will be.
Bring a book, game, puzzle, music, or other entertainment to help pass the time.
Ask the office if it’s okay to bring a drink and snack with you in case you get hungry. 
Pay close attention to how you feel during an infusion, and make sure to tell your care team if you experience any discomfort. They know how to help. 
Consider setting up transportation to and from the infusion center. You will receive medicine before your infusion that may make you drowsy. If you need help setting up a ride, reach out to your family and friends.
Your care team will give you allergy medicine, a fever reducer, and a steroid to help reduce the risks of serious side effects from the infusion.
Wear loose clothes for comfort and so your care team can easily reach the infusion area of your body.

If you have any other questions about your infusions, ask your care team.

At-home care

Daily, at-home steps to manage your treatment experience

These steps may lower the chances of skin-related side effects, such as rash or infected skin around the nail or other side effects. Talk to your doctor about what steps are right for you.

medication red icon

Additional medicines

  • Oral antibiotics (for the first 3 months of treatment) followed by an antibiotic lotion for your scalp (for the next 9 months) may be prescribed to reduce risk of skin-related side effects
  • Medicine to lower your risk of blood clots will be prescribed for the first 4 months of treatment

Make sure to tell your doctor about any other medicines you are taking. Consider using a pill box to help you organize your medicines.

Mild, ceramide-based moisturizer (such as La Roche-Posay Lipikar or CeraVe†‡)

Use on your face and body (except scalp) at least once a day.

Limit direct exposure to sunlight

Wear protective clothing and broad-spectrum sunscreen with SPF ≥30.

finger red icon

Antiseptic cleanser (such as chlorhexidine 4%)

Use to wash your hands and feet once a day.

†Talk to your doctor about what is right for you.

‡All trademarks are property of their respective owners.

Other tips to help throughout treatment

  • Consider bathing/
    showering with warm or cool water (not hot water)
  • Use mild soaps and shampoos for sensitive
    skin
  • Use laundry detergents made for sensitive skin and without perfumes
  • Wear soft, loose-fitting clothing
  • Wear gloves during activities that could cause nail infection (for example, cleaning)
  • Eat a balanced diet
  • Talk to your doctor about activities that feel right for you
  • Seek out support from your family, friends, care team, and/or support groups

Talk to your care team to understand if these tips are right for you.

Tracking side effects

Your care team can help manage or reduce the risk of RYBREVANT® side effects

It's important to tell your care team about side effects right away if you:

  • First experience symptoms of side effects
  • Feel that the side effects are affecting daily activities
  • Have been treating side effects according to your doctor's instructions but they do not improve

Pausing, decreasing the dose, or stopping treatment may be needed in some cases to help manage side effects.

medication red icon

Tell your doctor if you are pregnant or plan to become pregnant. RYBREVANT® infusions and LAZCLUZE® can harm your unborn baby.

Before treatment

Tips to help you prepare for your RYBREVANT FASPRO™ injection appointments

Drink plenty of water the day before, and have a good breakfast on injection day.
Wear loose clothes for comfort and so your care team can easily reach your abdomen or stomach.
Pay close attention to how you feel during an injection, and make sure to tell your care team if you experience any discomfort. They know how to help.
Your care team will give you allergy medicine, a fever reducer, and a steroid to help reduce the risks of serious side effects from the injection.
Consider setting up transportation to and from your appointment. You will receive medicine before your injection that may make you drowsy. If you need help setting up a ride, reach out to your family and friends.

If you have any other questions about your injections, ask your care team.

At-home care

Daily, at-home steps to manage your treatment experience

These steps may lower the chances of skin-related side effects, such as rash or infected skin around the nail or other side effects. Talk to your doctor about what steps are right for you.

medication red icon

Additional medicines

  • Oral antibiotics (for the first 3 months of treatment) followed by an antibiotic lotion for your scalp (for the next 9 months) may be prescribed to reduce risk of skin-related side effects
  • Medicine to lower your risk of blood clots will be prescribed for the first 4 months of treatment

Make sure to tell your doctor about any other medicines you are taking. Consider using a pill box to help you organize your medicines.

Mild, ceramide-based moisturizer (such as La Roche-Posay Lipikar or CeraVe†‡)

Use on your face and body (except scalp) at least once a day.

Limit direct exposure to sunlight

Wear protective clothing and broad-spectrum sunscreen with SPF ≥30.

finger red icon

Antiseptic cleanser (such as chlorhexidine 4%)

Use to wash your hands and feet once a day.

†Talk to your doctor about what is right for you.

‡All trademarks are property of their respective owners.

Other tips to help throughout treatment

  • Consider bathing/
    showering with warm or cool water (not hot water)
  • Use mild soaps and shampoos for sensitive
    skin
  • Use laundry detergents made for sensitive skin and without perfumes
  • Wear soft, loose-fitting clothing
  • Wear gloves during activities that could cause nail infection (for example, cleaning)
  • Eat a balanced diet
  • Talk to your doctor about activities that feel right for you
  • Seek out support from your family, friends, care team, and/or support groups

Talk to your care team to understand if these tips are right for you.

During treatment

Your care team can help manage or reduce the risk of RYBREVANT FASPRO™ side effects

It's important to tell your care team about side effects right away if you:

  • First experience symptoms of side effects
  • Feel that the side effects are affecting daily activities
  • Have been treating side effects according to your doctor's instructions but they do not improve

Pausing, decreasing the dose, or stopping treatment may be needed in some cases to help manage side effects.

medication red icon

Tell your doctor if you are pregnant or plan to become pregnant. RYBREVANT FASPRO™ injections and LAZCLUZE® can harm your unborn baby.

Before each infusion

Tips to help you prepare for your RYBREVANT® infusion appointments

Drink plenty of water the day before, and have a good breakfast on infusion day.
Bring a pillow and blanket for extra comfort.
Infusions can last several hours, so make sure you’ve set aside enough time for your appointment. Ask your care team about how long your infusion will be.
Bring a book, game, puzzle, music, or other entertainment to help pass the time.
Ask the office if it’s okay to bring a drink and snack with you in case you get hungry. 
Pay close attention to how you feel during an infusion, and make sure to tell your care team if you experience any discomfort. They know how to help. 
Consider setting up transportation to and from the infusion center. You will receive medicine before your infusion that may make you drowsy. If you need help setting up a ride, reach out to your family and friends.
Your care team will give you allergy medicine, a fever reducer, and a steroid to help reduce the risks of serious side effects from the infusion.
Wear loose clothes for comfort and so your care team can easily reach the infusion area of your body.

If you have any other questions about your infusions, ask your care team.

At-home care

Daily, at-home steps to manage your treatment experience

These steps may lower the chances of skin-related side effects, such as rash or infected skin around the nail or other side effects. Talk to your doctor about what steps are right for you.

medication red icon

Additional medicines

  • Oral antibiotics (for the first 3 months of treatment) followed by an antibiotic lotion for your scalp (for the next 9 months) may be prescribed to reduce risk of skin-related side effects
  • Medicine to lower your risk of blood clots will be prescribed for the first 4 months of treatment

Make sure to tell your doctor about any other medicines you are taking. Consider using a pill box to help you organize your medicines.

Mild, ceramide-based moisturizer (such as La Roche-Posay Lipikar or CeraVe†‡)

Use on your face and body (except scalp) at least once a day.

Limit direct exposure to sunlight

Wear protective clothing and broad-spectrum sunscreen with SPF ≥30.

finger red icon

Antiseptic cleanser (such as chlorhexidine 4%)

Use to wash your hands and feet once a day.

†Talk to your doctor about what is right for you.

‡All trademarks are property of their respective owners.

Other tips to help throughout treatment

  • Consider bathing/
    showering with warm or cool water (not hot water)
  • Use mild soaps and shampoos for sensitive
    skin
  • Use laundry detergents made for sensitive skin and without perfumes
  • Wear soft, loose-fitting clothing
  • Wear gloves during activities that could cause nail infection (for example, cleaning)
  • Eat a balanced diet
  • Talk to your doctor about activities that feel right for you
  • Seek out support from your family, friends, care team, and/or support groups

Talk to your care team to understand if these tips are right for you.

Tracking side effects

Your care team can help manage or reduce the risk of RYBREVANT® side effects

It's important to tell your care team about side effects right away if you:

  • First experience symptoms of side effects
  • Feel that the side effects are affecting daily activities
  • Have been treating side effects according to your doctor's instructions but they do not improve

Pausing, decreasing the dose, or stopping treatment may be needed in some cases to help manage side effects.

medication red icon

Tell your doctor if you are pregnant or plan to become pregnant. RYBREVANT® infusions and LAZCLUZE® can harm your unborn baby.

*Exon 19 deletion or exon 21 L858R substitution mutations.

EGFR+, mutated epidermal growth factor receptor; NSCLC, non–small cell lung cancer.

Man and woman meeting with a doctor; questions to ask your doctor
Man and woman meeting with a doctor; questions to ask your doctor

Doctor Discussion Guide

Tips and example questions for having a helpful discussion with your doctor.

Elderly woman smiling happily outdoors
Elderly woman smiling happily outdoors

Savings & support

Once prescribed RYBREVANT FASPRO™ or RYBREVANT®, connect with a Care Navigator for your support needs.

The support and resources provided by RYBREVANT withMe are not intended to provide medical advice, replace a treatment plan you receive from your doctor or nurse, or serve as a reason for you to start or stay on treatment.

Man rubbing his arm
Man rubbing his arm

About side effects

There are side effects that you may experience during treatment with RYBREVANT FASPRO™ + LAZCLUZE® or RYBREVANT® + LAZCLUZE®.