Discover the range of dosing options designed to meet your needs
Regardless of the dosing schedule you follow, it doesn't change how the medicine works in your body.
Talk to your doctor about which option may be best for you.
RYBREVANT FASPRO™ offers once-a-month
or twice-a-month dosing options.
You have the option to receive RYBREVANT FASPRO™ just once each month after the first 4 injections, which are given weekly.
RYBREVANT® offers twice-a-month
dosing options.
RYBREVANT® is given twice each month following the first 4 infusions, which are given weekly.
Choose the tab for your treatment below to see how treatment is given.
RYBREVANT FASPRO™ is given as a rapid ~5-minute injection(s) under the skin (subcutaneous) in the stomach area (abdomen)
How you'll get the injections
You’ll be given injections by your healthcare provider at your doctor's office.
Your care team will also give you additional medications and take time to make sure you’re doing well before you leave your visit.
Your treatment plan
Your doctor will decide the appropriate dose of RYBREVANT FASPRO™ based on your body weight and determine how often you will get injections.
See sample dosing schedule below.
Taking RYBREVANT
FASPRO™ with LAZCLUZE®
Additional medications
- Before each RYBREVANT FASPRO™ injection, your doctor will give you medicines—such as allergy medicine, medicine to reduce fever, and a steroid—to help lower the risk of certain side effects
- They may also prescribe oral and/or topical antibiotics to reduce the risk of skin-related side effects. Learn more about additional at-home care tips to help protect your skin during treatment
- Your doctor will also start you on medicine to prevent blood clots for the first 4 months of treatment
RYBREVANT FASPRO™ offers 2 dosing options to suit your schedule
Weeks 1-4
- When you start treatment, you will get 1 injection each week for 4 weeks
- Injections will be given over the course of ~5 minutes (this is how long the injection takes; total time of care team visit varies)
Week 5 and on
- If your doctor recommends a once-a-month dosing plan: Starting on Week 5 and moving forward, you’ll get 2 injections (given over the course of ~5 minutes each) during your once-monthly visit
- If your doctor recommends a twice-a-month dosing plan: Starting on Week 5 and moving forward, you’ll get 1 injection (given over the course of ~5 minutes) every 2 weeks
- Your doctor will monitor your progress and adjust treatment accordingly until disease progression or unacceptable toxicity
RYBREVANT® is an infusion given into your vein through an intravenous (IV) line
How you'll get the RYBREVANT® infusion
You’ll be given infusions at your doctor’s office or an infusion center.
Your care team will also give you additional medications and take time to make sure you're doing well before you leave your visit.
Your treatment plan
Your doctor will decide the appropriate dose of RYBREVANT® based on your body weight and determine how often you will get infusions.
See sample dosing schedule below.
Taking RYBREVANT® with LAZCLUZE®
RYBREVANT® infusions, be
sure to take LAZCLUZE®
ahead of time.
Additional medications
- Before each RYBREVANT® infusion, your doctor will give you medicines—such as allergy medicine, medicine to reduce fever, and a steroid—to help lower the risk of certain side effects
- They may also prescribe oral and/or topical antibiotics to reduce the risk of skin-related side effects. Learn more about additional at-home care tips to help protect your skin during treatment
- Your doctor will also start you on medicine to prevent blood clots for the first 4 months of treatment
RYBREVANT® infusion schedule recommendation
Week 1
- Your first dose of RYBREVANT® will be split across 2 days
- Your first infusions can take about 4 to 8 hours
- Your dose may be adjusted to help manage possible side effects
Weeks 2-5
- After your first week, you’ll get 1 infusion each week for the next 4 weeks
- RYBREVANT® infusions will take about 2 hours, starting on Week 2 and for the rest of treatment
Week 6
- You will not get an infusion on Week 6
Week 7 and on
- Starting on Week 7 and moving forward, you’ll get 1 infusion every 2 weeks
- Your doctor will monitor your progress and adjust treatment accordingly until disease progression or unacceptable toxicity
If you are currently receiving RYBREVANT®, ask your doctor if RYBREVANT FASPRO™ is right for you.
RYBREVANT FASPRO™ is given as a rapid ~5-minute injection(s) under the skin (subcutaneous) in the stomach area (abdomen)
How you'll get the injections
You’ll be given injections by your healthcare provider at your doctor's office.
Your care team will also give you additional medications and take time to make sure you’re doing well before you leave your visit.
Your treatment plan
Your doctor will decide the appropriate dose of RYBREVANT FASPRO™ based on your body weight and determine how often you will get injections.
See sample dosing schedule below.
Taking RYBREVANT
FASPRO™ with LAZCLUZE®
Additional medications
- Before each RYBREVANT FASPRO™ injection, your doctor will give you medicines—such as allergy medicine, medicine to reduce fever, and a steroid—to help lower the risk of certain side effects
- They may also prescribe oral and/or topical antibiotics to reduce the risk of skin-related side effects. Learn more about additional at-home care tips to help protect your skin during treatment
- Your doctor will also start you on medicine to prevent blood clots for the first 4 months of treatment
RYBREVANT FASPRO™ offers 2 dosing options to suit your schedule
Weeks 1-4
- When you start treatment, you will get 1 injection each week for 4 weeks
- Injections will be given over the course of ~5 minutes (this is how long the injection takes; total time of care team visit varies)
Week 5 and on
- If your doctor recommends a once-a-month dosing plan: Starting on Week 5 and moving forward, you’ll get 2 injections (given over the course of ~5 minutes each) during your once-monthly visit
- If your doctor recommends a twice-a-month dosing plan: Starting on Week 5 and moving forward, you’ll get 1 injection (given over the course of ~5 minutes) every 2 weeks
- Your doctor will monitor your progress and adjust treatment accordingly until disease progression or unacceptable toxicity
RYBREVANT® is an infusion given into your vein through an intravenous (IV) line
How you'll get the RYBREVANT® infusion
You’ll be given infusions at your doctor’s office or an infusion center.
Your care team will also give you additional medications and take time to make sure you're doing well before you leave your visit.
Your treatment plan
Your doctor will decide the appropriate dose of RYBREVANT® based on your body weight and determine how often you will get infusions.
See sample dosing schedule below.
Taking RYBREVANT® with LAZCLUZE®
RYBREVANT® infusions, be
sure to take LAZCLUZE®
ahead of time.
Additional medications
- Before each RYBREVANT® infusion, your doctor will give you medicines—such as allergy medicine, medicine to reduce fever, and a steroid—to help lower the risk of certain side effects
- They may also prescribe oral and/or topical antibiotics to reduce the risk of skin-related side effects. Learn more about additional at-home care tips to help protect your skin during treatment
- Your doctor will also start you on medicine to prevent blood clots for the first 4 months of treatment
RYBREVANT® infusion schedule recommendation
Week 1
- Your first dose of RYBREVANT® will be split across 2 days
- Your first infusions can take about 4 to 8 hours
- Your dose may be adjusted to help manage possible side effects
Weeks 2-5
- After your first week, you’ll get 1 infusion each week for the next 4 weeks
- RYBREVANT® infusions will take about 2 hours, starting on Week 2 and for the rest of treatment
Week 6
- You will not get an infusion on Week 6
Week 7 and on
- Starting on Week 7 and moving forward, you’ll get 1 infusion every 2 weeks
- Your doctor will monitor your progress and adjust treatment accordingly until disease progression or unacceptable toxicity
If you are currently receiving RYBREVANT®, ask your doctor if RYBREVANT FASPRO™ is right for you.
*Exon 19 deletion or exon 21 L858R substitution mutations.
LAZCLUZE® is a 240-mg once-a-day pill
You can take at home or
wherever
is convenient
On your own schedule
With or without food
Take LAZCLUZE® exactly as your doctor tells you
- Swallow the LAZCLUZE® pill whole. Do not crush, cut, or chew the pill
- If you miss a pill and it has been less than 12 hours, take the missed pill. If it has been more than 12 hours, skip the pill and take your next pill at your regularly scheduled time
- If you vomit a dose of LAZCLUZE®, do not take an extra dose. Take your next dose at your regularly scheduled time
- On the days you get a RYBREVANT FASPRO™ injection or RYBREVANT® infusion, be sure to take LAZCLUZE® before your injection or infusion
EGFR+, mutated epidermal growth factor receptor; NSCLC, non–small cell lung cancer.
