Your care team is here to help—together, you can find ways to manage side effects you may experience from your treatment
Let your care team know about any side effects right away, if you:
Notice new symptoms
Feel that side effects are making daily activities harder
Have side effects that aren’t getting better, even after following your doctor’s advice
Everyone’s experience is different. Tell your doctor right away if you have any of the side effects listed below.
Choose the tab for your treatment below to learn more about possible side effects.
Learn more about possible serious side effects of RYBREVANT FASPRO™, including:
Allergic and injection-related reactions are common with RYBREVANT FASPRO™ and can be severe or serious.
Tell your doctor right away if you have any of these symptoms during or after your injection:
- Shortness of breath
- Fever
- Chills
- Flushing (skin that feels hot or looks red)
- Chest discomfort (pain or tightness)
- Dizziness or lightheadedness
- Vomiting
RYBREVANT FASPRO™ can cause serious lung problems, which can be life-threatening. The symptoms may feel similar to your lung cancer symptoms.
Tell your doctor right away if you have any new or worsening symptoms of lung problems including:
- Shortness of breath
- Cough
- Fever
You may experience severe rash.
Tell your doctor right away if you have any of these symptoms:
- Blisters
- Peeling
- Skin pain and sores
- Redness
- Raised acne-like bumps
- Itching
- Dry skin
If you notice skin problems: Your doctor may start you on an antibiotic for the first 3 months of treatment followed by an antibiotic lotion for your scalp for the next 9 months. During treatment with RYBREVANT FASPRO™, you should apply a mild, ceramide-based moisturizer on your face and body (except scalp) at least once a day and wash your hands and feet once a day with 4% chlorhexidine solution. Your doctor may send you to see a skin specialist (dermatologist).
What you can do: Taking certain steps can help lower your risk of skin-related side effects. Watch this video or click here for a downloadable guide of tips and reminders to use during treatment.
You may experience eye problems.
Tell your doctor right away if you have any of these symptoms:
- Eye pain
- Inflammation of eyelids
- Dry eyes
- Eye redness
- Blurred vision
- Changes in vision
- Itchy eyes
- Excessive tearing (watery eyes)
- Sensitivity to light
If you notice eye problems: Your doctor may send you to see an eye specialist (ophthalmologist).
What you can do: You should not use contact lenses until your eye symptoms are checked by a doctor.
RYBREVANT FASPRO™ can harm your unborn baby.
Tell your doctor right away if you become pregnant or think you might be pregnant.
What you can do: If you or your partner are able to become pregnant, you should both use effective birth control during treatment and for 3 months after your final dose of RYBREVANT FASPRO™.
If you are breastfeeding or plan to breastfeed, it is not known if RYBREVANT FASPRO™ passes into your breast milk. Do not breastfeed during treatment and for 3 months after your last dose of RYBREVANT FASPRO™.
The most common side effects of RYBREVANT® which may be experienced with RYBREVANT FASPRO™ injections, are listed below:
- Rash
- Infected skin around your nail
- Muscle and joint pain
- Shortness of breath
- Nausea (feeling sick to your stomach)
- Swelling of hands, ankles, feet, face, or all of your body
- Cough
- Feeling very tired
- Sores in your mouth
- Constipation
- Vomiting
- Changes in certain blood tests
Your care team can help manage or reduce the risk of side effects to help you stay on treatment.
Learn more about possible serious side effects of RYBREVANT®, including:
Reactions during the infusion are common. Some reactions can be serious or life-threatening, such as severe allergic reaction (anaphylaxis). Most reactions happen during the first infusion.
Tell your doctor right away if you have any of these symptoms during your infusion:
- Shortness of breath, trouble breathing, or wheezing
- Chest discomfort (pain or tightness)
- Swelling in your eyes, lips, or tongue
- Fever
- Chills
- Numbness in your tongue, lips, cheeks, or gums
- Flushing (skin that feels hot or looks red)
- Skin rash, hives, or itchy skin
- Nausea (feeling sick to your stomach) or vomiting
- Stomach cramps
- Feeling dizzy, lightheaded, or faint
- Headache
If you have a reaction during your infusion, your care team may change or pause your treatment to help with your symptoms.
RYBREVANT® may cause serious lung problems, which can be life-threatening. The symptoms may feel similar to your lung cancer symptoms.
Tell your doctor right away if you notice any new or worsening lung symptoms, including:
- Shortness of breath
- Cough
- Fever
You may experience severe rash.
Tell your doctor right away if you have any of these symptoms:
- Blisters
- Peeling
- Skin pain and sores
- Redness
- Raised, acne-like bumps
- Itching
- Dry skin
If you notice skin problems: Your doctor may start you on an antibiotic for the first 3 months of treatment followed by an antibiotic lotion for your scalp for the next 9 months. During treatment with RYBREVANT®, you should apply a mild, ceramide-based moisturizer on your face and body (except scalp) at least once a day and wash your hands and feet once a day with 4% chlorhexidine solution. Your doctor may send you to see a skin specialist (dermatologist).
What you can do: Taking certain steps can help lower your risk of skin-related side effects. Watch this video or click here for a downloadable guide of tips and reminders to use during treatment.
You may experience eye problems.
Tell your doctor right away if you have any of these symptoms:
- Eye pain
- Swollen eyelids
- Dry eyes
- Eye redness
- Blurred vision
- Changes in vision
- Itchy eyes
- Excessive tearing (watery eyes)
- Sensitivity to light
If you notice eye problems:notice eye problems: Your doctor may send you to see an eye specialist (ophthalmologist).
What you can do: You should not use contact lenses until your eye symptoms are checked by a doctor.
RYBREVANT® can harm your unborn baby.
Tell your doctor right away if you become pregnant or think you might be pregnant.
What you can do: If you or your partner are able to become pregnant, you should both use effective birth control during treatment and for 3 months after your final dose of RYBREVANT®.
If you are breastfeeding or plan to breastfeed, it is not known if RYBREVANT® passes into your breast milk. Do not breastfeed during treatment and for 3 months after your last dose of RYBREVANT®.
The most common side effects of RYBREVANT® include:
- Rash
- Infected skin around your nail
- Infusion-related reactions
- Muscle and joint pain
- Shortness of breath
- Nausea (feeling sick to your stomach)
- Feeling very tired
- Swelling in your hands, ankles, feet, face, or all of your body
- Sores in your mouth
- Cough
- Constipation
- Vomiting
- Changes in certain blood tests
Your care team can help manage or reduce the risk of side effects to help you stay on treatment.
Learn more about possible serious side effects of RYBREVANT FASPRO™, including:
Allergic and injection-related reactions are common with RYBREVANT FASPRO™ and can be severe or serious.
Tell your doctor right away if you have any of these symptoms during or after your injection:
- Shortness of breath
- Fever
- Chills
- Flushing (skin that feels hot or looks red)
- Chest discomfort (pain or tightness)
- Dizziness or lightheadedness
- Vomiting
RYBREVANT FASPRO™ can cause serious lung problems, which can be life-threatening. The symptoms may feel similar to your lung cancer symptoms.
Tell your doctor right away if you have any new or worsening symptoms of lung problems including:
- Shortness of breath
- Cough
- Fever
You may experience severe rash.
Tell your doctor right away if you have any of these symptoms:
- Blisters
- Peeling
- Skin pain and sores
- Redness
- Raised acne-like bumps
- Itching
- Dry skin
If you notice skin problems: Your doctor may start you on an antibiotic for the first 3 months of treatment followed by an antibiotic lotion for your scalp for the next 9 months. During treatment with RYBREVANT FASPRO™, you should apply a mild, ceramide-based moisturizer on your face and body (except scalp) at least once a day and wash your hands and feet once a day with 4% chlorhexidine solution. Your doctor may send you to see a skin specialist (dermatologist).
What you can do: Taking certain steps can help lower your risk of skin-related side effects. Watch this video or click here for a downloadable guide of tips and reminders to use during treatment.
You may experience eye problems.
Tell your doctor right away if you have any of these symptoms:
- Eye pain
- Inflammation of eyelids
- Dry eyes
- Eye redness
- Blurred vision
- Changes in vision
- Itchy eyes
- Excessive tearing (watery eyes)
- Sensitivity to light
If you notice eye problems: Your doctor may send you to see an eye specialist (ophthalmologist).
What you can do: You should not use contact lenses until your eye symptoms are checked by a doctor.
RYBREVANT FASPRO™ can harm your unborn baby.
Tell your doctor right away if you become pregnant or think you might be pregnant.
What you can do: If you or your partner are able to become pregnant, you should both use effective birth control during treatment and for 3 months after your final dose of RYBREVANT FASPRO™.
If you are breastfeeding or plan to breastfeed, it is not known if RYBREVANT FASPRO™ passes into your breast milk. Do not breastfeed during treatment and for 3 months after your last dose of RYBREVANT FASPRO™.
The most common side effects of RYBREVANT® which may be experienced with RYBREVANT FASPRO™ injections, are listed below:
- Rash
- Infected skin around your nail
- Muscle and joint pain
- Shortness of breath
- Nausea (feeling sick to your stomach)
- Swelling of hands, ankles, feet, face, or all of your body
- Cough
- Feeling very tired
- Sores in your mouth
- Constipation
- Vomiting
- Changes in certain blood tests
Your care team can help manage or reduce the risk of side effects to help you stay on treatment.
Learn more about possible serious side effects of RYBREVANT®, including:
Reactions during the infusion are common. Some reactions can be serious or life-threatening, such as severe allergic reaction (anaphylaxis). Most reactions happen during the first infusion.
Tell your doctor right away if you have any of these symptoms during your infusion:
- Shortness of breath, trouble breathing, or wheezing
- Chest discomfort (pain or tightness)
- Swelling in your eyes, lips, or tongue
- Fever
- Chills
- Numbness in your tongue, lips, cheeks, or gums
- Flushing (skin that feels hot or looks red)
- Skin rash, hives, or itchy skin
- Nausea (feeling sick to your stomach) or vomiting
- Stomach cramps
- Feeling dizzy, lightheaded, or faint
- Headache
If you have a reaction during your infusion, your care team may change or pause your treatment to help with your symptoms.
RYBREVANT® may cause serious lung problems, which can be life-threatening. The symptoms may feel similar to your lung cancer symptoms.
Tell your doctor right away if you notice any new or worsening lung symptoms, including:
- Shortness of breath
- Cough
- Fever
You may experience severe rash.
Tell your doctor right away if you have any of these symptoms:
- Blisters
- Peeling
- Skin pain and sores
- Redness
- Raised, acne-like bumps
- Itching
- Dry skin
If you notice skin problems: Your doctor may start you on an antibiotic for the first 3 months of treatment followed by an antibiotic lotion for your scalp for the next 9 months. During treatment with RYBREVANT®, you should apply a mild, ceramide-based moisturizer on your face and body (except scalp) at least once a day and wash your hands and feet once a day with 4% chlorhexidine solution. Your doctor may send you to see a skin specialist (dermatologist).
What you can do: Taking certain steps can help lower your risk of skin-related side effects. Watch this video or click here for a downloadable guide of tips and reminders to use during treatment.
You may experience eye problems.
Tell your doctor right away if you have any of these symptoms:
- Eye pain
- Swollen eyelids
- Dry eyes
- Eye redness
- Blurred vision
- Changes in vision
- Itchy eyes
- Excessive tearing (watery eyes)
- Sensitivity to light
If you notice eye problems:notice eye problems: Your doctor may send you to see an eye specialist (ophthalmologist).
What you can do: You should not use contact lenses until your eye symptoms are checked by a doctor.
RYBREVANT® can harm your unborn baby.
Tell your doctor right away if you become pregnant or think you might be pregnant.
What you can do: If you or your partner are able to become pregnant, you should both use effective birth control during treatment and for 3 months after your final dose of RYBREVANT®.
If you are breastfeeding or plan to breastfeed, it is not known if RYBREVANT® passes into your breast milk. Do not breastfeed during treatment and for 3 months after your last dose of RYBREVANT®.
The most common side effects of RYBREVANT® include:
- Rash
- Infected skin around your nail
- Infusion-related reactions
- Muscle and joint pain
- Shortness of breath
- Nausea (feeling sick to your stomach)
- Feeling very tired
- Swelling in your hands, ankles, feet, face, or all of your body
- Sores in your mouth
- Cough
- Constipation
- Vomiting
- Changes in certain blood tests
Your care team can help manage or reduce the risk of side effects to help you stay on treatment.
Prepare for your best possible treatment experience
Taking extra steps to reduce the risk of certain side effects can make a real difference in your treatment experience.
Certain side effects may also decrease as you continue treatment. In a study of RYBREVANT® + LAZCLUZE®, common side effects—including rash, nail toxicity, low albumin levels, acne, and mouth inflammation—usually happened during the first 4 months of treatment and became less frequent over time.
Make sure to check in with your care team about how you're feeling during treatment, so that they can help make sure you're on the dose that supports your best possible results.
EGFR+, mutated epidermal growth factor receptor; NSCLC, non–small cell lung cancer.
